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医学部公共卫生学院
School of Public Health,Medical College of Soochow University
江苏省老年病预防与转化医学重点实验室
Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases
A lysine-to-arginine mutation on NEDD8 markedly reduces the activity of cullin RING E3 ligase through the impairment of neddylation cascades.